Thomas M Magin Selected Research

Keratin-5 (Keratin 5)

1/2020	Disease-associated keratin mutations reduce traction forces and compromise adhesion and collective migration.
6/2019	Treatment of keratinocytes with 4-phenylbutyrate in epidermolysis bullosa: Lessons for therapies in keratin disorders.
1/2018	Threonine 150 Phosphorylation of Keratin 5 Is Linked to Epidermolysis Bullosa Simplex and Regulates Filament Assembly and Cell Viability.
10/2015	Distinct Impact of Two Keratin Mutations Causing Epidermolysis Bullosa Simplex on Keratinocyte Adhesion and Stiffness.
8/2015	A Drosophila Model of Epidermolysis Bullosa Simplex.
3/2006	Loss-of-function mutations in the keratin 5 gene lead to Dowling-Degos disease.

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Thomas M Magin Research Topics

Disease

10	Epidermolysis Bullosa Simplex (Epidermolysis Bullosa Herpetiformis Dowling Meara) 12/2022 - 01/2007
7	Inflammation (Inflammations) 06/2019 - 12/2007
7	Neoplasms (Cancer) 01/2019 - 11/2004
3	Neoplasm Metastasis (Metastasis) 02/2015 - 01/2013
2	Epidermolysis Bullosa 06/2019 - 06/2015
2	Infections 01/2019 - 01/2019
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 10/2015 - 07/2002
2	Cataract (Cataracts) 03/2009 - 11/2008
2	Dowling-Degos Disease 12/2007 - 03/2006
2	Hyperpigmentation 12/2007 - 03/2006
2	Liver Diseases (Liver Disease) 08/2007 - 05/2006
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 12/2022
1	Systemic Mastocytosis 12/2022
1	Wounds and Injuries (Trauma) 11/2020
1	Dysostoses 01/2020
1	Premature Aging 01/2020
1	Liver Neoplasms (Liver Cancer) 02/2019
1	Carcinogenesis 01/2019
1	Contagious Ecthyma 01/2019
1	Skin Diseases (Skin Disease) 01/2018
1	Pemphigus (Pemphigus Vulgaris) 01/2018
1	Fibrosis (Cirrhosis) 08/2015
1	Cardiomyopathies (Cardiomyopathy) 08/2015
1	Necrosis 08/2015
1	Melanoma (Melanoma, Malignant) 05/2014
1	Adenocarcinoma 01/2013
1	Lung Neoplasms (Lung Cancer) 01/2013
1	Cystic Fibrosis (Mucoviscidosis) 11/2012
1	Inborn Genetic Diseases (Disease, Hereditary) 10/2012
1	Body Weight (Weight, Body) 06/2012
1	Porphyrias (Porphyria) 06/2012
1	Spontaneous Abortion (Miscarriage) 04/2011
1	Hyperoxia 04/2011
1	Hypoxia (Hypoxemia) 04/2011
1	Proteostasis Deficiencies 04/2010
1	Epidermolysis Bullosa Dystrophica (Dystrophic Epidermolysis Bullosa) 09/2009
1	Pancreatic Neoplasms (Pancreatic Cancer) 08/2006
1	Chronic Pancreatitis 05/2006
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 05/2006
1	End Stage Liver Disease 05/2006
1	Alexander Disease (Alexander's Disease) 01/2006
1	Glioma (Gliomas) 12/2005
1	Neuroblastoma 12/2005
1	Tetraploidy 03/2005
1	Papilloma (Papillomatosis) 11/2004

Drug/Important Bio-Agent (IBA)

26	Keratins (Keratin)IBA 12/2022 - 07/2002
6	Keratin-5 (Keratin 5)IBA 01/2020 - 03/2006
6	Proteins (Proteins, Gene)FDA Link 10/2015 - 11/2004
4	VimentinIBA 01/2020 - 11/2008
4	Keratin-14 (Keratin 14)IBA 01/2020 - 08/2015
3	K-18 conjugate (K18)IBA 11/2012 - 05/2006
2	Protein AggregatesIBA 06/2019 - 11/2008
2	DesmogleinsIBA 01/2018 - 08/2015
2	Mitogen-Activated Protein KinasesIBA 05/2014 - 11/2004
2	CytokinesIBA 09/2009 - 05/2009
2	AntibodiesIBA 09/2009 - 08/2006
1	midostaurinIBA 12/2022
1	Phosphotransferases (Kinase)IBA 12/2022
1	4-phenylbutyric acid (Buphenyl)FDA Link 06/2019
1	Keratin-8 (Keratin 8)IBA 02/2019
1	Viral ProteinsIBA 01/2019
1	Cell Adhesion MoleculesIBA 01/2019
1	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 01/2019
1	loricrinIBA 01/2019
1	Proliferating Cell Nuclear Antigen (PCNA)IBA 01/2019
1	Pharmaceutical PreparationsIBA 01/2019
1	Interleukin-6 (Interleukin 6)IBA 01/2019
1	Insulin ReceptorIBA 01/2019
1	Differentiation AntigensIBA 01/2019
1	Threonine (L-Threonine)FDA Link 01/2018
1	AutoantibodiesIBA 01/2018
1	Type II Keratins (Type II Keratin)IBA 01/2018
1	Desmoglein 2IBA 08/2015
1	Connexin 43 (Connexin43)IBA 08/2015
1	PlectinIBA 06/2015
1	Small Interfering RNA (siRNA)IBA 05/2014
1	Protein Kinases (Protein Kinase)IBA 05/2014
1	enzastaurinIBA 05/2014
1	Cre recombinaseIBA 01/2013
1	Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)IBA 11/2012
1	Desmoplakins (Desmoplakin)IBA 10/2012
1	EnzymesIBA 06/2012
1	BilirubinIBA 06/2012
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 04/2011
1	CollagenIBA 09/2009
1	UbiquitinIBA 11/2008
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 11/2008
1	Proteasome Endopeptidase Complex (Proteasome)IBA 11/2008
1	Amino Acids FDA Link 05/2006
1	DNA (Deoxyribonucleic Acid)IBA 05/2006
1	Dichlorodiphenyldichloroethane (DDD)IBA 03/2006
1	Bisbenzimidazole (Hoechst 33258)IBA 12/2005
1	Keratin-18 (Keratin 18)IBA 03/2005
1	Acetates (Acetic Acid Esters)FDA Link 11/2004
1	anthraceneIBA 11/2004
1	Keratin-10IBA 11/2004

Therapy/Procedure

4	Therapeutics 12/2022 - 03/2009
1	Cell- and Tissue-Based Therapy (Cell Therapy) 09/2009
1	Intradermal Injections 09/2009